Research Fields

Electromyographic and temperature measurements in the contracted human skeletal muscle. Pharmacological, physiological and biochemical studies on endogenous opioid functions, including pain control, intestinal motility and secretion, gastric secretion, and release of endogenous opioids. Muscarinic receptor binding studies in the rat cerebral cortex and heart. Characterization of muscarinic receptors in the isolated mouse stomach. Participation in the development of irreversible and reversible gastric proton pump inhibitors, in particular pantoprazole. Voltage clamp experiments on the opioid receptor subtypes involved in the control of intestinal chloride secretion. Participation in microbiological sudies on Helicobacter pylori.