Born in 1943. Studies of human medicine. State examination in 1972. In 1973, Medical Doctor from W├╝rzburg University (Institute of Pharmacology and Toxicology), and lisence to practise medicine. Clinical experience from different hospitals from 1972 to 1976 in surgery, internal medicine, anaestesiology and neurology, last clinical appointment at the Clinic of Neurology, Munich University Hospital. Research scientist at the Institute of Pharmacology and Toxicology of Munich University since 1976. During this time cooperation with the Department of Neuropharmacology at the Max-Planck-Institute of Psychiatry, Munich. Lisence as a specialist in Pharmacology and Toxicology in 1980. Postdoctoral lecturing qualification for Pharmacology and Toxicology in 1981 (Dr. med. habil.). Appointment (permanent) as a Professor of Pharmacology at Hannover Medical School, Germany, in 1982. Sabbatical at the National Institute for Medical Research, Division of Physical Biochemistry, London, in 1984. Head of the Department Pharmacology- Gastroenterology at Altana Pharma AG Konstanz, Germany (now Takeda) since 1985. Appointment as an Extraordinary Professor of Pharmacology (apl. Prof.) at Hannover Medical School in 1987. Lisence as a specialist in Clinical Pharmacology since 1991. Medical expert opinions, both clinical and preclinical. During professional life member of the American Gastroenterological Association (AGA), the German Pharmacological and Toxicological Association, the International Narcotic Research Club, and the Editorial Board of the international journal ‘Pharmacology’.